If you or someone you know may be considering suicide or need help, call or text 988.
The latest group of dominant variants, called FLiRT variants (which include KP.3, KP.2, JN.1, and others), are grouped together because they have similar new mutations on their spike protein and have been outcompeting other variants to make up most of the cases in the U.S. this summer. The good news is that they don’t cause any major changes in symptoms from the other Omicron variants we’ve been seeing for the last couple of years. Symptoms tend to be more mild, but that’s mostly because of our increased immunity to the disease, not to the specific mutations themselves. Over the years, the average onset time of illness has gotten shorter, down from an average of 6.5 days to 3.4 for most Omicron subvariants, including these FLiRT variants. On the shorter end, symptoms can appear in as few as two days after exposure. While it’s still preliminary, Australia, New Zealand, and the U.K. are seeing FLiRT variants rising, and all had recent upticks in COVID cases. Whether that’s correlated is yet to be determined, but we are keeping an eye on rising wastewater positives, hospital visits, and cases in the U.S.
Sources: JHU, CDC, Osterholm Update
Whether or not to take Paxlovid if you’re COVID-positive is ultimately a decision you should make with your medical provider, but there are some things to keep in mind. First, you need to take it within five days of developing symptoms, though it works best the sooner you start taking it. You’ll also need a prescription, which generally means you need to qualify as high risk for developing severe COVID or have underlying conditions. Ultimately, there have been a number of studies that showed varying effectiveness for adults who take Paxlovid - even Pfizer’s own studies say it may not help people who are at low to moderate risk, who are fully vaccinated, and who have mild illness. For those at higher risk for severe disease and those who are unvaccinated, though, there is evidence that it can significantly reduce your risk of hospitalization and death. If you are unvaccinated or have higher risk factors, call your doctor right after you test positive to discuss the pros and cons and make a decision together.
Sources: Yale Medicine, Scientific American