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Early in the pandemic, people had no immunity to the novel virus, so our immune systems weren’t really fighting it. As a result, our viral load was highest around the day we started having symptoms. But as time goes on, and we’ve generally all been infected at least once, and many of us have been vaccinated a few times, our immune systems are fighting the virus as soon as it enters our body. So we have symptoms, but our immune response is keeping our viral load lower for a few days until around Day 4 when we have enough viral particles to test positive on a rapid test. Even when the isolation guidelines changed from 10 days to 5, we knew that some people would actually be infectious for longer. It was a calculated risk to balance keeping people safe and minimizing disruptions to their lives. That balancing act remains, and the likelihood of people adhering to a longer isolation period now seems slim. We recommend sticking with the 5-day guidelines for COVID positive people as long as they’re symptom-free upon returning to work.
Source: MedPage Today
Unfortunately, it probably does mean that the 5 days are here to stay, at least until the tide of public opinion turns so much that COVID is treated the way a cold was pre-pandemic, where it’s acceptable to get others sick. The reality right now, though, is that COVID is still much deadlier than the flu, not to mention much, MUCH deadlier than the common cold. So public health officials are not likely to touch the 5 day exclusion any time soon, at least until health outcomes after COVID infection become much better.
Source: CDC
Yes! This is the main takeaway from the recent study showing that people have the highest viral load on Day 4 after symptoms begin. The reality is that we’re not likely to see a change in the 5 day exclusions, but we can emphasize the importance that you’re not likely to test positive on a rapid test at home until your third or fourth (or even fifth) day after feeling sick. A negative test doesn’t mean much anymore unless you’ve taken it on days 3, 4, and 5 - which is why it’s important to stay home when you have COVID or flu-like symptoms, even if you test negative.
Source: MedPage Today